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| 中文名 | AF-353 ( Ro-4) |
| 英文名 | 2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]- |
| 别名 | 5-(5-碘-2-异丙基-4-甲氧基苯氧基)嘧啶-2,4-二胺;5-[5-碘-4-甲氧基-2-(1-甲基乙基)苯氧基]-2,4-嘧啶二胺 |
| CAS | 865305-30-2 |
| EINECS | |
| 化学式 | C14H17IN4O2 |
| 分子量 | 400.21 |
| inchi | |
| 包装信息 | 25 mg |
| 价格 | $259 |
| 产品描述 | AF-353 ( Ro-4) AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist. It is a highly potent inhibitor of α,β-meATP-evoked intracellular calcium flux in cell lines expressing recombinant rat and human P2X3 and human P2X2/3 channels. It also blocks human P2X2/3 channel function with marginally reduced potency (pIC50 = 7.3). It significantly reduces this parameter in both groups. It also reduces the inter-contractile interval in control but not in SCI rats. |
| 产品链接 | http://www.bocsci.com/product/af-353-cas-865305-30-2-459983.html |
| 更新日期 | 2025-04-30 11:27:47 |