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| 中文名 | Cilastatin ammonium salt |
| 英文名 | Cilastatin ammonium salt |
| 别名 | 西司他汀杂质;西司他丁杂质;西司他丁杂质15 |
| CAS | 877674-82-3 |
| EINECS | |
| 化学式 | C16H29N3O5S |
| 分子量 | 375.48 |
| inchi | |
| 包装信息 | 500 mg |
| 价格 | $1,099 |
| 产品描述 | Cilastatin ammonium salt Cilastatin Ammonium Salt is the ammonium salt of Cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects. |
| 产品链接 | http://www.bocsci.com/product/cilastatin-ammonium-salt-cas-877674-82-3-468925.html |
| 更新日期 | 2025-04-30 11:27:47 |