CZ415 BOC Sciences

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向其他CZ415供应商询盘

上海阿摩尔生物科技有限公司

品名: CZ415游离态
CAS: 1429639-50-8
规格: 99%
包装: 100mg；10mg；1g；1mg；250mg；25mg；50mg；5mg
价格: 电话、微信、QQ、邮件
产地: 上海
最后更新: 2026-01-29 09:24:04

北京索莱宝科技有限公司

品名: CZ-415
CAS: IC3110
规格: IC3110
包装: 5mg,瓶;10mg,瓶;50mg,瓶;100mg,瓶
价格: 电话、微信、QQ、邮件
产地: 北京
最后更新: 2026-01-29 08:43:52

上海麦克林生化科技股份有限公司

品名: CZ-415
CAS: 1429639-50-8
规格: C794004
包装: 1ml,1mg,5mg,25mg,100mg
价格: 641,179,280,359,878
最后更新: 2026-01-22 17:18:31

上海吉至生化科技有限公司

品名: CZ415
CAS: 1429639-50-8
包装: 25mg，5mg
价格: 面议、电联、微信、QQ
产地: 中国上海
最后更新: 2026-01-20 08:44:56

CZ415的基本信息

中文名	CZ415
英文名	CZ415
别名	化合物CZ415;CZ415游离态;MTOR抑制剂(CZ415)
CAS	1429639-50-8
EINECS	604-604-1
化学式	C22H29N5O4S
分子量	459.56
inchi
包装信息	5 mg
价格	$199
产品描述	CZ415 CZ415 is a highly selective potent mTOR inhibitor with little activity on other lipid and protein kinases with efficacy in a collagen induced arthritis model and exhibits excellent cell permeability. In the issue, Bergamini et al., who has identified CZ415, confirmed with its extraordinary selectivity, drug-like properties and proven efficacy in vivo, CZ415 represents an ideal molecule for the pharmacological investigation of mTOR pathophysiological role in vivo. Assessed in dose response format from HEK293T cells after treatment with CZ415: 1. inhibition of S6RP (downstream of mTORC1) phosphorylation in HEK293T: IC50 = 14.5 nM 产品描述 CZ415 CZ415 is a highly selective potent mTOR inhibitor with little activity on other lipid and protein kinases with efficacy in a collagen induced arthritis model and exhibits excellent cell permeability. In the issue, Bergamini et al., who has identified CZ415, confirmed with its extraordinary selectivity, drug-like properties and proven efficacy in vivo, CZ415 represents an ideal molecule for the pharmacological investigation of mTOR pathophysiological role in vivo. Assessed in dose response format from HEK293T cells after treatment with CZ415: 1. inhibition of S6RP (downstream of mTORC1) phosphorylation in HEK293T: IC50 = 14.5 nM 2. inhibition of Akt (mTORC2 substrate) phosphorylation in HEK293T: IC50 = 14.8 nM 3. inhibition of IFNγ release in stimulated human whole blood: IC50 = 226 nM
产品链接	http://www.bocsci.com/cz415-cas-1429639-50-8-item-474821.html
更新日期	2025-04-30 11:27:47