2-Hydroxy-4-methylpyridine
2-Hydroxy-4-methylpyridine
CAS: 13466-41-6;91914-05-5
Molecular Formula: C6H7NO
2-Hydroxy-4-methylpyridine - Names and Identifiers
2-Hydroxy-4-methylpyridine - Physico-chemical Properties
| Molecular Formula | C6H7NO |
| Molar Mass | 109.13 |
| Density | 1.1143 (rough estimate) |
| Melting Point | 131-134 °C (lit.) |
| Boling Point | 186-187 °C/12 mmHg (lit.) |
| Flash Point | 186-187°C/12mm |
| Appearance | White to light brown crystals |
| Color | White to Gray to Brown |
| BRN | 107082 |
| pKa | pK1:4.529(＋1) (25°C) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.5444 (estimate) |
| MDL | MFCD00134298 |
2-Hydroxy-4-methylpyridine - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R40 - Limited evidence of a carcinogenic effect |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S36 - Wear suitable protective clothing. S22 - Do not breathe dust. |
| WGK Germany | 3 |
| HS Code | 29333995 |
2-Hydroxy-4-methylpyridine - Introduction
2-Hydroxy-4-methylpyridine (abbreviated as 2-HMP) is an organic compound with the following properties and uses:
Nature:
1. Appearance: 2-HMP is a colorless to light yellow liquid.
2. Solubility: It is soluble in many organic solvents, such as alcohols, ethers and ketones.
3. Melting point and boiling point: The melting point of 2-HMP is -38 ℃, and the boiling point is 156-157 ℃.
4. chemical properties: 2-HMP is a basic compound, can occur acid-base reaction.
Use:
1. As an organic synthesis intermediate: 2-HMP can be used to synthesize various organic synthesis compounds, such as drugs, pesticides, dyes, etc.
2. As an oxidant: 2-HMP can be used as an oxidant in some reactions, such as oxidizing benzaldehyde to benzoic acid.
3. Used in surfactant manufacturing: 2-HMP can be used to synthesize certain surfactants, such as detergents.
Preparation Method:
There are many methods for preparing 2-HMP. The commonly used method is to obtain 2-HMP by oxidizing methyl pyrazine (methylpyrazine).
Safety Information:
1. 2-HMP is a flammable liquid, it is necessary to avoid contact with fire sources, and attention should be paid to fire and explosion prevention during storage.
2. When using 2-HMP, appropriate protective measures need to be taken, such as wearing protective gloves, goggles and protective clothing.
3. Avoid inhaling 2-HMP vapor. If you accidentally inhale or come into contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
4. 2-HMP needs to be kept away from children and pets, and stored away from fire sources and open flames.
Please note that the use and handling of chemicals require strict compliance with relevant safety operating procedures and regulations, and it is recommended to operate under professional supervision.
Nature:
1. Appearance: 2-HMP is a colorless to light yellow liquid.
2. Solubility: It is soluble in many organic solvents, such as alcohols, ethers and ketones.
3. Melting point and boiling point: The melting point of 2-HMP is -38 ℃, and the boiling point is 156-157 ℃.
4. chemical properties: 2-HMP is a basic compound, can occur acid-base reaction.
Use:
1. As an organic synthesis intermediate: 2-HMP can be used to synthesize various organic synthesis compounds, such as drugs, pesticides, dyes, etc.
2. As an oxidant: 2-HMP can be used as an oxidant in some reactions, such as oxidizing benzaldehyde to benzoic acid.
3. Used in surfactant manufacturing: 2-HMP can be used to synthesize certain surfactants, such as detergents.
Preparation Method:
There are many methods for preparing 2-HMP. The commonly used method is to obtain 2-HMP by oxidizing methyl pyrazine (methylpyrazine).
Safety Information:
1. 2-HMP is a flammable liquid, it is necessary to avoid contact with fire sources, and attention should be paid to fire and explosion prevention during storage.
2. When using 2-HMP, appropriate protective measures need to be taken, such as wearing protective gloves, goggles and protective clothing.
3. Avoid inhaling 2-HMP vapor. If you accidentally inhale or come into contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
4. 2-HMP needs to be kept away from children and pets, and stored away from fire sources and open flames.
Please note that the use and handling of chemicals require strict compliance with relevant safety operating procedures and regulations, and it is recommended to operate under professional supervision.
Last Update：2024-04-09 19:05:46
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