2-Bromopalmitic acid; 2-Bromopalmitate MedChemExpress (MCE)

Product Name	2-Bromohexadecanoic acid
Synonyms	2-bromopalmitate A-BROMOPALMITIC ACID 2-BROMOPALMITIC ACID ALPHA-BROMOPALMITATE Bromohexadecanoicacid 2-bromo-hexadecanoicaci 2-Bromohexadecanoic acid Synonyms 2-bromopalmitate A-BROMOPALMITIC ACID 2-BROMOPALMITIC ACID ALPHA-BROMOPALMITATE Bromohexadecanoicacid 2-bromo-hexadecanoicaci 2-Bromohexadecanoic acid 2-BROMOHEXADECANOIC ACID 2-BROMOHEXADECANOIC ACID (2-Bromopalmitic Acid)
CAS	18263-25-7
EINECS	242-137-0
Chemical Formula	C16H31BrO2
Molecular Weight	335.32
inchi
Package	10 mM * 1 mL;5 mg;10 mg;50 mg;100 mg
Price	Email to quote
Descriptions	2-Bromohexadecanoic acid 2-Bromohexadecanoic acid MedChemExpress (MCE) HY-111770 18263-25-7 2-Bromopalmitic acid Descriptions 2-Bromohexadecanoic acid 2-Bromohexadecanoic acid MedChemExpress (MCE) HY-111770 18263-25-7 2-Bromopalmitic acid 2-Bromopalmitate 99.95% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. 2-Bromohexadecanoic acid (2-Bromopalmitate 2-BP) is a palmitoylation inhibitor targeting DHHC (Asp-His-His-Cys) protein palmitoyltransferase. 2-Bromohexadecanoic acid inhibits palmitoylation of GSDME-C during pyroptosis and inhibits BAK/BAX-Caspase 3-GSDME pathway-mediated pyroptosis. Palmitoylation promotes the release of GSDME-C from GSDME-N after cleavage, and 2-BP inhibits the palmitoylation process, while inhibiting the modification of GSDME-C increases the interaction between GSDME-C and GSDME-N. 2-BP inhibits TNFa+CHX-induced apoptosis but not total cell death[1]. \| \| \| \| \| \| \| \| \| \| [1]. Hu L, et al. Chemotherapy-induced pyroptosis is mediated by BAK/BAX-caspase-3-GSDME pathway and inhibited by 2-bromopalmitate. Cell Death Dis. 2020 Apr 24 11(4):281. [Content Brief]
Supplier Website	http://www.medchemexpress.com/2-bromohexadecanoic-acid.html
Last Update	2025-10-14 16:03:33

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