Glycine MedChemExpress (MCE)

Product Name	Glycine
Synonyms	Gly Glycine H-Gly-OH glycocoll L-Glycine Glycine BP GLYCINE USP Synonyms Gly Glycine H-Gly-OH glycocoll L-Glycine Glycine BP GLYCINE USP BLOTTING BUFFER Aminoacetic acid GLYCINE TECHNICAL Glycine, Free Base USP24 GLYCINE USP24 Glycine (Food Grade) Glycine (Feed Grade) Glycine (Tech Grade) Glycine (Pharm Grade)
CAS	56-40-6
EINECS	200-272-2
Chemical Formula	C2H5NO2
Molecular Weight	75.07
inchi	InChI=1/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
Package	10 mM * 1 mL;10 mM * 1 mL;500 mg;500 mg;1 g;1 g
Price	Email to quote
Descriptions	Glycine Glycine MedChemExpress (MCE) HY-Y0966 56-40-6 99.93% Store at room temperature 3 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions Glycine Glycine MedChemExpress (MCE) HY-Y0966 56-40-6 99.93% Store at room temperature 3 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is orally active. Glycine can be used to study cell protection, cancer, neurological diseases, and angiogenesis. Glycine (0-1 mM, 0-48 h) has anti-tumor and anti-angiogenic effects. It can downregulate the production of VEGF in tumor cells HCT-116, HT-29 and CC-531, inhibit the growth of endothelial cells HUVEC through GlyR, and indirectly inhibit HUVEC migration and capillary formation[3]. Glycine (5 mM, 50 mM, 10 min) can prevent the aggregation of NINJ1 in the plasma membrane and inhibit cell death caused by the breakdown of NINJ1 dependent property membrane, thereby exerting its cytoprotective effect[4]. Glycine (single 40-800 mg/kg, i.p.) dose-dependently prevents scopolamine (HY-N0296)-induced social cognitive impairment in adult rats[2]. Glycine (500 and 1000 mg/kg/day for 14 days, i.p.) can significantly reduce kidney damage in lead-exposed mice by inhibiting ROS production[5]. Glycine (single 1 or 2 g/kg, p.o.) increases extracellular serotonin but not dopamine in the prefrontal cortex of rats NMDA Receptor Human Endogenous Metabolite Microbial Metabolite NINJ1 \| \| \| \| \| \| \| \| \| \| [1]. Johnson JW, et al. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature. 1987 Feb 5-11 325(6104):529-31. [Content Brief] [2]. Fone KCF, et al. Comparative Pro-cognitive and Neurochemical Profiles of Glycine Modulatory Site Agonists and Glycine Reuptake Inhibitors in the Rat: Potential Relevance to Cognitive Dysfunction and Its Management. Mol Neurobiol. 2020 May 57(5):2144-2166. [Content Brief] [3]. Bruns H, et al. Glycine inhibits angiogenesis in colorectal cancer: role of endothelial cells. Amino Acids. 2016 Nov 48(11):2549-2558. [Content Brief] [4]. Borges JP, et al. Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death. Elife. 2022 Dec 5 11:e78609. [Content Brief] [5]. Shafiekhani M, et al. Glycine supplementation mitigates lead-induced renal injury in mice. J Exp Pharmacol. 2019 Feb 18 11:15-22. [Content Brief] [6]. Bannai M, et al. Oral administration of glycine increases extracellular serotonin but not dopamine in the prefrontal cortex of rats. Psychiatry Clin Neurosci. 2011 Mar 65(2):142-9. [Content Brief]
Supplier Website	http://www.medchemexpress.com/2-Aminoacetic_acid.html
Last Update	2025-10-14 16:03:33

MedChemExpress (MCE) also provides

Lipopolysaccharides, from E. coli O55:B5

Category: Natural Products
CAS:
Last Update: 2025-10-14 16:03:33

(1R)-α-Pinene

Category: Natural Products
CAS: 7785-70-8
Last Update: 2025-10-14 16:03:33

Glycyl-L-glutamine

Category: Natural Products
CAS: 13115-71-4
Last Update: 2025-10-14 16:03:33

Triose phosphate

Category: Natural Products
CAS: 591-57-1
Last Update: 2025-10-14 16:03:33

Lactyl-CoA

Category: Natural Products
CAS: 1926-57-4
Last Update: 2025-10-14 16:03:33

12(S)-HPETE

Category: Natural Products
CAS: 71774-10-2
Last Update: 2025-10-14 16:03:33

Pyrithiamine

Category: Natural Products
CAS: 534-64-5
Last Update: 2025-10-14 16:03:33

alpha-CEHC

Category: Natural Products
CAS: 4072-32-6
Last Update: 2025-10-14 16:03:33


Supplier Name	MedChemExpress (MCE)
Contact	sales
Tel	609-228-6898
Mobile	609-228-6898
QQ
Email	sales@medchemexpress.com; tech@medchemexpress.com
Website	http://www.medchemexpress.com/
Wechat

Request for quotation

Supplier Contact