Citric acid trisodium MedChemExpress (MCE)

Product Name	Sodium citrate, anhydrous
Synonyms	Sodium citrate Trisodium citrate Sodium citrate, tribasic anhydrous Sodium Citrate Sodium Citrate anhydrous Sodium citrate, anhydrous trisodium citrate anhydrous Synonyms Sodium citrate Trisodium citrate Sodium citrate, tribasic anhydrous Sodium Citrate Sodium Citrate anhydrous Sodium citrate, anhydrous trisodium citrate anhydrous trisodium 2-hydroxypropane-1,2,3-tricarboxylate anhydrous
CAS	68-04-2
EINECS	200-675-3
Chemical Formula	C6H5Na3O7
Molecular Weight	258.07
inchi	InChI=1/C6H8O7.3Na/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3*+1/p-3
Package	100 mg;500 mg;1 g
Price	Email to quote
Descriptions	Citric acid trisodium Citric acid trisodium MedChemExpress (MCE) HY-B2201 68-04-2 Sodium citrate Descriptions Citric acid trisodium Citric acid trisodium MedChemExpress (MCE) HY-B2201 68-04-2 Sodium citrate Trisodium citrate anhydrous 98.0% Store at room temperature, keep dry and cool In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. Citric acid trisodium is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium causes renal toxicity in mice. Citric acid trisodium (0-12.5 mM 24 h) shows antiproliferative activity in a dose dependent manner[3]. Citric acid trisodium (12.5 mM 72 h) induces apoptosis and cell cycle arrest at G2/M phase and S phase in a dosedependent manner[3]. Citric acid trisodium (12.5 mM 48 h) increases the expression of FAS, BAX, BID, AIF, EndoG, cytochrome c, PARP, GADD153, GRP78 and caspase-3, -8, -9, and decreases of BCL-2 and BCL-Xl[3]. Citric acid trisodium (120, 240, and 480 mg/kg i.p.) significantly decreases GSH-Px activity and induces an increase in the MDA (malonyldialdehyde) levels in mouse liver[1]. Citric acid trisodium (120, 240, and 480 mg/kg i.p.) induces apoptosis by increases caspase-3 activity in a dose-dependent manner in mouse hepatocytes[1]. Citric acid trisodium (120, 240, and 480 mg/kg i.p. weekly for 3 weeks) causes renal toxicity in mice[2]. Human Endogenous Metabolite \| \| \| \| \| \| \| \| \| \| [1]. Chen X, et al. Study on injury effect of food additive citric acid on liver tissue in mice. Cytotechnology. 2014 Mar 66(2):275-82. [Content Brief] [2]. Chen X, Lv Q, Liu Y, Deng W. Effects of the food additive, citric acid, on kidney cells of mice. Biotech Histochem. 2015 Jan 90(1):38-44. [Content Brief] [3]. Ying TH, et al. Citric acid induces cell-cycle arrest and apoptosis of human immortalized keratinocyte cell line (HaCaT) via caspase- and mitochondrial-dependent signaling pathways. Anticancer Res. 2013 Oct 33(10):4411-20. [Content Brief]
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Last Update	2025-10-14 16:03:33

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