Holo-Bovine TransferrinHolo-Bovine Transferrin
MedChemExpress (MCE)
HY-P3267
11096-37-0
99.0%
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Room temperature in continental US
may vary elsewhere.
Holo-Bovine Transferrin, a blood-plasma glycoprotein, is a target ligand for transferrin receptor. Holo-Bovine Transferrin can bind to and mediate the transport of iron.
Holo-Bovine Transferrin (0.2, 1 and 5 μM, 30 min) enhances the enzymatic activity of thrombin[2]. Transferrins (0.2, 1 and 5 μM, 30 min) enhances the ability of thrombin and FXIIa to hydrolyze their natural substrates (fibrinogen)[2]. Transferrins can conjugate with cytochrome c, the conjugates can be uptaken by transferrin receptor overexpressing A549 cells, thereby inducing cell death[3].
Transferrin receptor[1] In Vitro Holo-Bovine Transferrin (0.2, 1 and 5 μM, 30 min) enhances the enzymatic activity of thrombin[2]. Transferrins (0.2, 1 and 5 μM, 30 min) enhances the ability of thrombin and FXIIa to hydrolyze their natural substrates (fibrinogen)[2]. Transferrins can conjugate with cytochrome c, the conjugates can be uptaken by transferrin receptor overexpressing A549 cells, thereby inducing cell death[3]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Holo-Bovine Transferrin Related Antibodies
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[1]. Li H, et al. Transferrin/transferrin receptor-mediated drug delivery. Med Res Rev. 2002 May
22(3):225-50. [Content Brief]
[2]. Tang X, et al. Transferrin plays a central role in coagulation balance by interacting with clotting factors. Cell Res. 2020 Feb
30(2):119-132. [Content Brief]
[3]. Saxena M, et al. Inducing cell death in vitro in cancer cells by targeted delivery of cytochrome c via a transferrin conjugate. PLoS One. 2018 Apr 12
13(4):e0195542. [Content Brief]