Lysozyme chlorideLysozyme chloride
MedChemExpress (MCE)
HY-B2237A
9066-59-5
Please store the product under the recommended conditions in the Certificate of Analysis.
Room temperature in continental US
may vary elsewhere.
Lysozyme chloride is a bactericidal enzyme, and it lyses gram-positive bacteria. Lysozyme chloride can also be used for the research of HIV infection and pulmonary emphysema.
Lysozyme is an ubiquitous enzyme. The hen egg is the most abundant source of Lysozyme, which constitutes approximately 3.4% of the albumen proteins. Lysozyme is a natural antimicrobial that hydrolyzes the β(1-4) glycosidic linkage between N-acetylmuramic acid and N-acetylglucosamine found in the peptidoglycan layer of the bacterial cell wall and causing cell lysis. The bactericidal effect of Lysozyme chloride is primarily limited to gram-positive bacteria, including pathogens such as Listeria monocytogenes and certain Clostridium species as well as some spoilage organisms, including thermophilic spore-forming bacteria and certain yeasts. The gram-negative bacteria are more resistant to Lysozyme chloride action because of their complex cell wall structure[1]. Lysozyme (1 mg/mL) chloride impairs the ability of hyaluronan (HA) to prevent elastase injury to elastic fibers[3].
Syrian hamsters exposes to aerosolized Lysozyme (20 mg in 20 ml of water
50 min) chloride prior to elastase administration showes significantly increased airspace enlargement[3].
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[1]. Banerjee P, et al. Influence of carbon dioxide on the activity of chicken egg white lysozyme. Poult Sci. 2011 Apr
90(4):889-95. [Content Brief]
[2]. Jing T, et al. Magnetic molecularly imprinted nanoparticles for recognition of lysozyme. Biosens Bioelectron. 2010 Oct 15
26(2):301-6. [Content Brief]
[3]. Cantor JO, et al. The effect of lysozyme on elastase-mediated injury. Exp Biol Med (Maywood). 2002 Feb
227(2):108-13. [Content Brief]