FITC-Dextran (MW 70000) MedChemExpress (MCE)

Product Name	FLUORESCEIN ISOTHIOCYANATE-DEXTRAN
Synonyms	FITC Dextran;FITC-Dextran 4;FITC-Dextran 70;FITC-Dextran 150;FITC–Dextran 2000;FLUORESCEIN ISOTHIOCYANATE-DEXTRAN
CAS	60842-46-8
EINECS
Chemical Formula
Molecular Weight
inchi
Package	1 mg;5 mg;10 mg;25 mg;50 mg
Price	Email to quote
Descriptions	FITC-Dextran (MW 70000) FITC-Dextran (MW 70000) MedChemExpress (MCE) HY-128868E 60842-46-8 4°C, protect from light In solvent : -80°C, 6 months Descriptions FITC-Dextran (MW 70000) FITC-Dextran (MW 70000) MedChemExpress (MCE) HY-128868E 60842-46-8 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. FITC-Dextran (MW 70000) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments. FITC-Dextran (MW 70000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm Em=525 nm). FITC-Dextran (MW 70000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 70000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption[1][2][3]. Storage: protect from light. Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).For intestinal barrier function assay[5]1. Fast mice for 4 h.2. Orally gavage mice with FITC-Dextran MW 70000 (0.6 mg/g).3. Measure fluorescence intensity of plasma in 4 h (excitation nm/emission 520 nm). \| \| \| \| \| \| \| \| \| \| [1]. Moumaris M, et al. Fluorescein isothiocyanate-dextran can track apoptosis and necrosis induced by heat shock of peripheral blood mononuclear cells and HeLa cells[J]. Open Biological Sciences Journal, 2015, 1(1). [2]. Natarajan R, et al. Fluorescein Isothiocyanate (FITC)-Dextran Extravasation as a Measure of Blood-Brain Barrier Permeability. Curr Protoc Neurosci. 2017 Apr 10 79:9.58.1-9.58.15. [Content Brief] [3]. Eriksson I, et al. Analysis of Lysosomal pH by Flow Cytometry Using FITC-Dextran Loaded Cells. Methods Mol Biol. 2017 1594:179-189. [Content Brief] [4]. Okabayashi K, et al. Cdc42 activates paracellular transport in polarised submandibular gland cells. Arch Oral Biol. 2021 Dec 132:105276. [Content Brief] [5]. Yu W, et al. ACE2 contributes to the maintenance of mouse epithelial barrier function. Biochem Biophys Res Commun. 2020 Dec 17 533(4):1276-1282. [Content Brief]
Supplier Website	http://www.medchemexpress.com/fitc-dextran-mw-70000.html
Last Update	2025-10-14 16:03:33

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