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Supplier NameMedChemExpress (MCE)
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Product Name4-Aminophenylmercuric acetate
Synonyms4-(Acetoxymercuri)aniline
p-(acetoxymercuri)aniline
p-(Acetoxymercuric)aniline
P-(ACETOXYMERCURIC)ANILINE
4-aminophenylmercuriacetate
4-aminophenylmercury acetate
4-Aminophenylmercuric acetate

Synonyms

4-(Acetoxymercuri)aniline
p-(acetoxymercuri)aniline
p-(Acetoxymercuric)aniline
P-(ACETOXYMERCURIC)ANILINE
4-aminophenylmercuriacetate
4-aminophenylmercury acetate
4-Aminophenylmercuric acetate
P-AMINOPHENYLMERCURIC ACETATE
(acetato)(p-aminophenyl)mercury
(acetato)(p-aminophenyl)-mercur
(acetato-o)(4-aminophenyl)-mercur
(4-aminophenyl)mercury(1+) acetate
CAS6283-24-5
EINECS228-497-1
Chemical FormulaC8H9HgNO2
Molecular Weight351.75
inchiInChI=1/C6H6N.C2H4O2.Hg/c7-6-4-2-1-3-5-6;1-2(3)4;/h2-5H,7H2;1H3,(H,3,4);/q;;+1/p-1/rC6H6HgN.C2H4O2/c7-5-1-3-6(8)4-2-5;1-2(3)4/h1-4H,8H2;1H3,(H,3,4)/q+1;/p-1
Package10 mM * 1 mL;50 mg;100 mg
PriceEmail to quote
Descriptionsp-Aminophenylmercuric acetate

p-Aminophenylmercuric acetate

MedChemExpress (MCE)

HY-148905

6283-24-5

99.07%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

p-Aminophenylmercuric acetate

p-Aminophenylmercuric acetate

MedChemExpress (MCE)

HY-148905

6283-24-5

99.07%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

p-Aminophenylmercuric acetate is an organomercurial activator of matrix metalloproteinases (MMP). P-Aminophenylmercuric acetate participates in the activation and inhibition of MMP-8 by attacking protein sulfhydryl or inducing cysteine switching reaction. p-Aminophenylmercuric acetate promotes the shedding of betacellulin precursor (pro-BTC). p-Aminophenylmercuric acetate influences the binding of agonists and antagonists to the opiate receptor.

p-Aminophenylmercuric acetate (APMA) (0-30 µM
20 min) decreases the apparent number of dihydromorphine binding sites and increases the sensitivity of agonist binding to the inhibitory effects of sodium in rat brain homogenate[2]. p-Aminophenylmercuric acetate (0.5 mM
30 min) activates the MMP-2 and MMP-9[3].

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[1]. Sanderson M P, et al. ADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx[J]. Journal of Biological Chemistry, 2005, 280(3): 1826-1837. [Content Brief]

[2]. PASTERNAK G W, et al. Differential effects of protein-modifying reagents on receptor binding of opiate agonists and antagonists[J]. Molecular Pharmacology, 1975, 11(3): 340-351. [Content Brief]

[3]. Gendron R, et al. Inhibition of the activities of matrix metalloproteinases 2, 8, and 9 by chlorhexidine[J]. Clinical Diagnostic Laboratory Immunology, 1999, 6(3): 437-439. [Content Brief]

Supplier Websitehttp://www.medchemexpress.com/p-aminophenylmercuric-acetate.html
Last Update2025-10-14 16:03:33
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