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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttp://www.medchemexpress.com/
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Product NameLysophosphatidylcholines (egg) (Lyso-Lecithins (egg))
SynonymsLysophosphatidylcholines (egg);Lysophosphatidylcholines (egg) (Lyso-Lecithins (egg))
CAS9008-30-4
EINECS
Chemical FormulaC24H50NO7P (for palmitoyl)
Molecular Weight495.6
inchi
Package1 mg;5 mg;10 mg;25 mg;50 mg;100 mg
PriceEmail to quote
DescriptionsLysophosphatidylcholines

Lysophosphatidylcholines

MedChemExpress (MCE)

HY-139414

9008-30-4

99.0%

Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

Lysophosphatidylcholines

Lysophosphatidylcholines

MedChemExpress (MCE)

HY-139414

9008-30-4

99.0%

Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

Lysophosphatidylcholines is an orally active lysolipid and a component of oxidized low density lipoprotein (LDL). Lysophosphatidylcholines induces cell injury, the production of IL-1β and apoptosis. Lysophosphatidylcholines has a proactive effect on sepsis.

Lysophosphatidylcholine (3-100 μM, 24 h) reduced HUVEC viability[1]. Lysophosphatidylcholines (12.5μM, 4 h) upregulates gene expression of IL-1β in human peripheral blood monocytes[2]. Lysophosphatidylcholines (75μM, 24 h) induces apoptosis in HUVEC through a p38-mitogen-activated protein kinase-dependent mechanism[3].

Lysophosphatidylcholines (0.1-20 mg/kg, Oral, single dose) protects against sepsis-induced lethality on albino ICR mice[4]. Lysophosphatidylcholines (0.1-20 mg/kg, Oral, single dose) enhances bacterial clearance, blocks cecal ligation and puncture (CLP)-induced neutrophil deactivation and increases bactericidal activity of neutrophils[4].

IL-1β ERK1 ERK2

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[1]. Kim E A, et al. Lysophosphatidylcholine induces endothelial cell injury by nitric oxide production through oxidative stress [J]. The Journal of Maternal-Fetal & Neonatal Medicine, 2009, 22(4): 325-331. [Content Brief]

[2]. Liu-Wu Y, et al. Lysophosphatidylcholine induces the production of IL-1β by human monocytes [J]. Atherosclerosis, 1998, 137(2): 351-357. [Content Brief]

[3]. Takahashi M, et al. Lysophosphatidylcholine induces apoptosis in human endothelial cells through a p38-mitogen-activated protein kinase-dependent mechanism [J]. Atherosclerosis, 2002, 161(2): 387-394. [Content Brief]

[4]. Yan J J, et al. Therapeutic effects of lysophosphatidylcholine in experimental sepsis [J]. Nature medicine, 2004, 10(2): 161-167. [Content Brief]

Supplier Websitehttp://www.medchemexpress.com/lysophosphatidylcholines.html
Last Update2025-10-14 16:03:33
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