Citric acid monohydrate MedChemExpress (MCE)

Product Name	Citric acid monohydrate
Synonyms	citric CITRIC ACID H2O Citricacidhydrate Citric acid Mono Hydrous citric acid Citric acid hydrate Citronensαure-hydrat Synonyms citric CITRIC ACID H2O Citricacidhydrate Citric acid Mono Hydrous citric acid Citric acid hydrate Citronensαure-hydrat Citric acid Monohydride Citric acid monohydrate Citric acid, monohydrate Citric Acid Monohydrate BP HYDROXYTRICARBALLYLIC ACID MONOHYDRATE BETA-HYDROXY-TRICARBOXYLIC ACID MONOHYDRATE citric acid free acid monohydrate*crystalline 2,3-propanetricarboxylicacid,2-hydroxy-monohydrate 1,2,3-Propanetricarboxylicacid,2-hydroxy-,monohydrate 2-Hydroxy-1,2,3,propane-tricarboxylic acid, monohydrate 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, monohydrate
CAS	5949-29-1
EINECS	200-662-2
Chemical Formula	C6H10O8
Molecular Weight	210.1388
inchi	InChI=1/C6H8O7.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);1H2
Package	5 g;10 g
Price	Email to quote
Descriptions	Citric acid monohydrate Citric acid monohydrate MedChemExpress (MCE) HY-N1428A 5949-29-1 98.0% Store at room temperature, keep dry and cool In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions Citric acid monohydrate Citric acid monohydrate MedChemExpress (MCE) HY-N1428A 5949-29-1 98.0% Store at room temperature, keep dry and cool In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. Citric acid monohydrate is a natural preservative and food tartness enhancer. Citric acid monohydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid monohydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid monohydrate causes renal toxicity in mice. Citric acid monohydrate (0-12.5 mM 24 h) shows antiproliferative activity in a dose dependent manner[3]. Citric acid monohydrate (12.5 mM 72 h) induces apoptosis and cell cycle arrest at G2/M phase and S phase in a dosedependent manner[3]. Citric acid monohydrate (12.5 mM 48 h) increases the expression of FAS, BAX, BID, AIF, EndoG, cytochrome c, PARP, GADD153, GRP78 and caspase-3, -8, -9, and decreases of BCL-2 and BCL-Xl[3]. Citric acid monohydrate (120, 240, and 480 mg/kg i.p.) significantly decreases GSH-Px activity and induces an increase in the MDA (malonyldialdehyde) levels in mouse liver[1]. Citric acid monohydrate (120, 240, and 480 mg/kg i.p.) induces apoptosis by increases caspase-3 activity in a dose-dependent manner in mouse hepatocytes[1]. Citric acid monohydrate (120, 240, and 480 mg/kg i.p. weekly for 3 weeks) causes renal toxicity in mice[2]. Human Endogenous Metabolite \| \| \| \| \| \| \| \| \| \| [1]. Chen X, et al. Study on injury effect of food additive citric acid on liver tissue in mice. Cytotechnology. 2014 Mar 66(2):275-82. [Content Brief] [2]. Chen X, Lv Q, Liu Y, Deng W. Effects of the food additive, citric acid, on kidney cells of mice. Biotech Histochem. 2015 Jan 90(1):38-44. [Content Brief] [3]. Ying TH, et al. Citric acid induces cell-cycle arrest and apoptosis of human immortalized keratinocyte cell line (HaCaT) via caspase- and mitochondrial-dependent signaling pathways. Anticancer Res. 2013 Oct 33(10):4411-20. [Content Brief]
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Last Update	2025-10-14 16:03:33

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