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Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoateMCE China:Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate
Brand:MedChemExpress (MCE)
Cat. No.HY-153137
CAS:1566559-80-5
Synonyms:304O13
Purity:98.71%
Storage:-20°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months
-20°C, 1 month (protect from light, stored under nitrogen)
Shipping:Room temperature in continental US
may vary elsewhere.
Description:Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate is a biodegradable lipid prepared by the conjugate addition of alkylamines to acrylates. Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate can be used in various drug delivery systems to deliver polynucleotides, siRNA for example.
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References:
[1]. Anderson, et al. Amine-containing lipid nanoparticles for delivery of siRNA. World Intellectual Property Organization, WO2014028487 A1. 2014-02-20.
[2]. Whitehead KA, Dorkin JR, Vegas AJ, et al. Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity. Nat Commun. 2014
5:4277.  
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