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MCE China：PLGA-PEG-PLGA (hydrogel) (LA:GA 7:1)
Brand：MedChemExpress (MCE)
Cat. No.HY-156829B
Storage：Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Shipping：Room temperature in continental US
may vary elsewhere.
Description：PLGA-PEG-PLGA (hydrogel) (LA:GA 7:1) is a biodegradable thermosensitive hydrogel product that can undergo phase transition at a specific temperature. PLGA-PEG-PLGA (hydrogel) (LA:GA 7:1) can be widely used in drug delivery systems, tissue engineering, wound dressings, and biosensors. The gelation temperature varies with concentration. The higher the concentration, the lower the gelation temperature. The gelation temperature is between 31-34℃ at a concentration of 15-20 wt%.
In Vitro：Gel preparation method: (1) Take the solid raw material out of the freezing environment, return it to room temperature, remove the condensed water on the outer packaging and then open it
(2) According to the gel use environment, add phosphate buffer, complete culture medium or distilled water and other solvents into the bottle to prepare a 15-20% (w/w) solution
(3) Stir at room temperature in a cool environment (≤25°C) for 24 hours until the polymer is completely dissolved to obtain a thermosensitive hydrogel
(4) Cool the prepared thermosensitive hydrogel to 4°C, and then filter and sterilize it with a 0.22 µm polyethersulfone syringe filter under a sterile environment. Note: (1) Generally, the gelling temperature of isotonic solutions such as phosphate buffer and complete culture medium is about 1-2°C lower than that of distilled water
(2) After adding solvent and during dissolution, scrape the gelled solid from the bottle wall, bottle cap, etc. with a scraper or other tools several times to make it fully contact with the solvent, which can accelerate the dissolution of the polymer.
Trachelogenin |
Rabeprazole (sodium) |
Atenolol |
Selonsertib |
Butylphthalide |
Rhein |
Se-Methylselenocysteine |
Bilirubin |
Salmeterol |
MRT67311Trending products：Recombinant Proteins
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Natural Products
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Fluorescent Dye
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PROTAC
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Isotope-Labeled Compounds
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Oligonucleotides
References：
[1]. Gao Y, et al. PLGA-PEG-PLGA hydrogel for ocular drug delivery of dexamethasone acetate. Drug Dev Ind Pharm. 2010 Oct
36(10):1131-8.
[Content Brief]
Brand introduction:
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MCE (MedChemExpress) has a global exclusive compound library of more than 200 kinds, and we are committed to providing the most comprehensive range of high-quality small molecule active compounds for scientific research customers around the world；
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More than 50,000 highly selective inhibitors and agonists are involved in various popular signaling pathways and disease areas；
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The products cover a variety of recombinant proteins, peptides, commonly used kits, more PROTAC, ADC and other characteristic products, widely used in new drug research and development, life science and other scientific research projects；
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Provide virtual screening, ion channel screening, metabolomics analysis detection analysis, drug screening and other professional technical services；
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It has a professional experimental center and strict quality control and verification system；
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Provide LC/MS, NMR, HPLC, chiral analysis, elemental analysis and other quality inspection reports to ensure the high purity and high quality of products；
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The biological activity of the products has been verified by the experiments of customers in various countries；
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A variety of top journals such as Nature, Cell, Science and pharmaceutical patents have included the scientific research results of MCE customers；
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Our professional team tracks the latest pharmaceutical and life science research and provides you with the latest active compounds in the world；
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It has established long-term cooperation with the world's major pharmaceutical companies and well-known scientific research institutions。
