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  3. Drug Derivative
  4. 1-Hydroxyrutecarpine

1-Hydroxyrutecarpine  (Synonyms: 1-Hydroxyrutaecarpine)

目录号: HY-N1631
产品使用指南 技术支持

1-Hydroxyrutaecarpine (compound 1a) 是芸香果苷的羟基衍生物。1-Hydroxyrutaecarpine 表现出细胞毒性，P-388 和 HT-29 细胞的 ED50 值分别为 3.72 和 7.44 µg/mL。

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1-Hydroxyrutecarpine

1-Hydroxyrutecarpine Chemical Structure

CAS No. : 53600-24-1

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规格 价格 是否有货 数量
1 mg ￥11000
1 - 2 周
5 mg   询价  
10 mg   询价  

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1-Hydroxyrutecarpine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

1-Hydroxyrutaecarpine (compound 1a) is a hydroxy-derivative of rutaecarpine. 1-Hydroxyrutaecarpine shows cytotoxicities with ED50s of 3.72, 7.44 µg/mL for P-388 and HT-29 cells, respectively. 1-Hydroxyrutaecarpine shows antiplatelet activity[1][2][3].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HT-29 IC50
24.7 μM
Compound: 51
Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTT assay
[PMID: 36375335]
P388 IC50
12.4 μM
Compound: 51
Antiproliferative activity against mouse P388 cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay
Antiproliferative activity against mouse P388 cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay
[PMID: 36375335]
分子量

303.31

Formula

C18H13N3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

1-Hydroxyrutecarpine 相关分类

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  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1-Hydroxyrutecarpine53600-24-11-HydroxyrutaecarpineDrug DerivativeDrug derivativeantiplateletrutaecarpineP-388HT-29 cellscytotoxicitiesInhibitorinhibitorinhibit

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