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1-Naphthylacetamide  (Synonyms: 1-萘乙酰胺; NAAM; 1-Naphthaleneacetamide; α-Naphthylacetamide)

目录号: HY-19699
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1-Naphthylacetamide 是一种口服有效的非甾体抗炎剂 (NAIA),同时也是一种吲哚类生长素类植物生长调节剂。1-Naphthylacetamide 可抑制炎症反应相关通路、调节植物激素信号传导过程,兼具抗炎、局部麻醉、解痉挛、缓解疼痛、利尿活性。1-Naphthylacetamide 能促进植物细胞扩大、分化及果实膨大。1-Naphthylacetamide 还可导致小鼠中枢神经系统 (CNS) 抑制,表现为自发活动减少、易激惹性降低、身体肌张力下降,以及耳廓反射、同侧屈肌反射和角膜反射减弱[1][2]

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1-Naphthylacetamide

1-Naphthylacetamide Chemical Structure

CAS No. : 86-86-2

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生物活性

1-Naphthylacetamide is an orally active nonsteroidal anti-inflammatory agent (NAIA) and also an indole-type auxin plant growth regulator. 1-Naphthylacetamide inhibits inflammatory response-related pathways and modulates plant hormone signaling, exhibiting anti-inflammatory, local anesthetic, antispasmodic, analgesic, and diuretic activities. 1-Naphthylacetamide promotes plant cell expansion, differentiation, and fruit enlargement. Additionally, 1-Naphthylacetamide induces central nervous system (CNS) depression in mice, characterized by reduced spontaneous activity, decreased irritability, decreased muscle tone, and attenuated ear-cuff reflex, ipsilateral flexor reflex, and corneal reflex[1][2].

IC50 & Target

Brassinolide

 

体外研究
(In Vitro)

1-Naphthylacetamide 衍生物在体外表现出明显的局部麻醉作用[1]

1-Naphthylacetamide 的衍生物(10 μg/mL)在体外具有解痉活性,与标准试剂 Atropine (HY-B1205) 具有可比性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

185.23

Formula

C12H11NO

CAS 号
性状

固体

中文名称

1-萘乙酰胺

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
纯度 & 产品资料
参考文献
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
1-Naphthylacetamide
目录号:
HY-19699
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