2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 21-Deoxy Cortisone

21-Deoxy Cortisone  (Synonyms: 21-Desoxycortisone; NSC 38722)

目录号: HY-W741510
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21-Deoxy Cortisone (21-Desoxycortisone; NSC 38722)是 11-酮孕酮的皮质类固醇代谢物。它由 11-酮孕酮通过细胞色素 P450 (CYP) 同工酶 CYP17A1 形成，但也可以通过 21-脱氧皮质醇 (HY-113405) 被 11β-羟基类固醇脱氢酶 2 型 (11β-HSD2) 氧化而产生。先天性肾上腺增生症是一种先天性代谢缺陷，其特征是缺乏 21-羟化酶，21-Deoxy Cortisone 水平在患有先天性肾上腺增生症的患者中会升高。

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21-Deoxy Cortisone

21-Deoxy Cortisone Chemical Structure

CAS No. : 1882-82-2

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5 mg ￥1040
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10 mg ￥1656
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21-Deoxy Cortisone 相关抗体

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生物活性

21-Deoxy Cortisone (21-Desoxycortisone; NSC 38722) is a corticosteroid metabolite of 11-ketoprogesterone. It is formed from 11-ketoprogesterone by the cytochrome P450 (CYP) isozyme CYP17A1, but can also be produced by oxidation of 21-deoxycortisone (HY-113405) by 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2). Congenital adrenal hyperplasia is an inborn error of metabolism characterized by a deficiency of 21-hydroxylase, and 21-Deoxy Cortisone levels are elevated in patients with congenital adrenal hyperplasia.

分子量

344.44

Formula

C₂₁H₂₈O₄
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

21-Deoxy Cortisone 相关分类

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Keywords:

21-Deoxy Cortisone1882-82-221-Desoxycortisone NSC 38722NSC38722NSC 38722NSC-38722Endogenous MetaboliteInhibitorinhibitorinhibit

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