2. Membrane Transporter/Ion Channel
  3. GLUT
  4. 3-Deoxy-3-fluoro-D-fructose

3-Deoxy-3-fluoro-D-fructose (Compound 12) 是一种 2,5-Anhydro-D-mannitol 衍生物。3-Deoxy-3-fluoro-D-fructose 是一种用于己糖转运蛋白 5 (GLUT5) 的选择性探针。3-Deoxy-3-fluoro-D-fructose 可抑制 GLUT5 对 14C 标记的 D-果糖的转运，在 EMT-6 和 MCF-7 细胞中的 IC50 分别为 1.16 µM 和 2.37 µM。3-Deoxy-3-fluoro-D-fructose 可用于癌症的正电子发射断层扫描 (PET) 成像。

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3-Deoxy-3-fluoro-D-fructose

3-Deoxy-3-fluoro-D-fructose Chemical Structure

CAS No. : 110925-86-5

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3-Deoxy-3-fluoro-D-fructose 相关抗体

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生物活性

3-Deoxy-3-fluoro-D-fructose (Compound 12) is a derivative of 2,5-Anhydro-D-mannitol. 3-Deoxy-3-fluoro-D-fructose is a selective probe of Hexose transporter 5 (GLUT5). 3-Deoxy-3-fluoro-D-fructose inhibits the transport of D-fructose labeled with 14C by GLUT5 with IC50s of 1.16 and 2.37 µM in EMT-6 and MCF-7 cells. 3-Deoxy-3-fluoro-D-fructose can be used for positron emission tomography (PET) imaging of cancers[1].

分子量

182.15

Formula

C6H11FO5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

3-Deoxy-3-fluoro-D-fructose 相关分类

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Keywords:

3-Deoxy-3-fluoro-D-fructose110925-86-5GLUTGlucose transporter2,5-Anhydro-D-mannitolHexose transporter 5GLUT5EMT-6 cellsMCF-7 cellsPET imagingCancersInhibitorinhibitorinhibit

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