2. Metabolic Enzyme/Protease
  3. MMP Lipoxygenase Tyrosinase
  4. 3-Hydroxy-2-pyrone

3-Hydroxy-2-pyrone (Compound 12d) 是一种金属酶抑制剂。3-Hydroxy-2-pyrone 在 1 mM 的浓度下，对基质金属蛋白酶 (MMP) 的抑制率约为 50%，对非血红素铁酶 5-脂氧合酶 (5-LOX) 的抑制率超过 70%。3-Hydroxy-2-pyrone 对铜依赖性酶酪氨酸酶 (tyrosinase) 也具有一定的抑制活性。3-Hydroxy-2-pyrone 可用于癌症、感染和炎症相关的研究。

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3-Hydroxy-2-pyrone

3-Hydroxy-2-pyrone Chemical Structure

CAS No. : 496-64-0

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规格 价格 是否有货 数量
50 mg ￥116
In-stock
100 mg ￥186
In-stock
250 mg ￥379
In-stock
500 mg ￥583
In-stock
1 g ￥874
In-stock
5 g ￥4193
In-stock
10 g ￥5999
In-stock
50 g   询价  

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3-Hydroxy-2-pyrone 相关抗体

Top Publications Citing Use of Products

查看 MMP 亚型特异性产品:

查看所有亚型
MMP-1 MMP-2 MMP-3 MMP-8 MMP-9 MMP-13 MMP-14 MMP-17 ADAM10 ADAM17 MMP-7 MMP-12 MMP-10 MMP ADAM8 MMP-19

查看 Lipoxygenase 亚型特异性产品:

查看所有亚型
5-LOX 12-LOX 15-LOX

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

3-Hydroxy-2-pyrone (Compound 12d) is a metalloenzyme inhibitor. 3-Hydroxy-2-pyrone shows an inhibition rate of approximately 50% for matrix metalloproteinases (MMP) and the inhibition rate for non-heme iron enzyme 5-lipoxygenase (5-LOX) was over 70% at 1 mM. 3-Hydroxy-2-pyrone also has certain inhibitory activity against copper-dependent enzyme tyrosinase. 3-Hydroxy-2-pyrone can be used for the research of cancer, infection and inflammation[1].

分子量

112.08

Formula

C5H4O3
CAS 号
性状

固体

颜色

White to light brown

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
纯度 & 产品资料

纯度: 99.61%

COA (292 KB) HNMR (131 KB) GC (214 KB)

产品使用指南 (1538 KB)
参考文献

3-Hydroxy-2-pyrone 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

3-Hydroxy-2-pyrone496-64-0MMPLipoxygenaseTyrosinaseMatrix metalloproteinasesLOXInhibitorinhibitorinhibit

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