2. Apoptosis
  3. Apoptosis
  4. 7-Ketositosterol

7-Ketositosterol 是一种植物甾醇，能从桑树 (Morus alba L.) 果实中分离得到。7-Ketositosterol 可显著抑制 Cisplatin (HY-17394) 诱导的 LLC-PK1 细胞凋亡 (apoptosis)，具有改善 Cisplatin 诱导的肾毒性的潜力。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

7-Ketositosterol

7-Ketositosterol Chemical Structure

CAS No. : 2034-74-4

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
5 mg ￥584
In-stock
10 mg ￥1112
In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

7-Ketositosterol 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

7-Ketositosterol is a phytosterol isolated from the fruits of the mulberry tree (Morus alba L.). 7-Ketositosterol can significantly inhibit Cisplatin (HY-17394)-induced apoptosis in LLC-PK1 cells and has the potential to improve Cisplatin-induced nephrotoxicity[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
> 20 μg/mL
Compound: 8
Cytotoxicity against human A549 cells
Cytotoxicity against human A549 cells
[PMID: 23511021]
BV-2 IC50
> 100 μM
Compound: 36
Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs in presence of LPS by Griess reaction based assay
Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs in presence of LPS by Griess reaction based assay
[PMID: 28911817]
HT-29 IC50
48 μM
Compound: 29
Cytotoxicity against human HT-29 cells after 48 hrs by Alamar blue assay
Cytotoxicity against human HT-29 cells after 48 hrs by Alamar blue assay
[PMID: 20931970]
Hep 3B2 IC50
> 20 μg/mL
Compound: 8
Cytotoxicity against human Hep3B cells
Cytotoxicity against human Hep3B cells
[PMID: 23511021]
HepG2 IC50
> 20 μg/mL
Compound: 8
Cytotoxicity against human HepG2 cells
Cytotoxicity against human HepG2 cells
[PMID: 23511021]
MCF7 IC50
> 20 μg/mL
Compound: 8
Cytotoxicity against human MCF7 cells
Cytotoxicity against human MCF7 cells
[PMID: 23511021]
MDA-MB-231 IC50
> 20 μg/mL
Compound: 8
Cytotoxicity against human MDA-MB-231 cells
Cytotoxicity against human MDA-MB-231 cells
[PMID: 23511021]
分子量

428.69

Formula

C29H48O2
CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验： 

DMF 中的溶解度 : 12 mg/mL (27.99 mM; 超声加热助溶)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.3327 mL 11.6634 mL 23.3269 mL
5 mM 0.4665 mL 2.3327 mL 4.6654 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

7-Ketositosterol 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMF 1 mM 2.3327 mL 11.6634 mL 23.3269 mL 58.3172 mL
5 mM 0.4665 mL 2.3327 mL 4.6654 mL 11.6634 mL
10 mM 0.2333 mL 1.1663 mL 2.3327 mL 5.8317 mL
15 mM 0.1555 mL 0.7776 mL 1.5551 mL 3.8878 mL
20 mM 0.1166 mL 0.5832 mL 1.1663 mL 2.9159 mL
25 mM 0.0933 mL 0.4665 mL 0.9331 mL 2.3327 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

7-Ketositosterol2034-74-4ApoptosisLLC-PK1MAPKsMorus albamulberrynephrotoxicityphytosterolsInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
7-Ketositosterol
目录号：
HY-N2757
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

>
  • 四川省
  • 上海市

    • T

    X

    Y

    Z

    热 A B C F G H J L N Q S T X Y Z