1. Signaling Pathways
  2. Membrane Transporter/Ion Channel
  3. GLUT

GLUT (葡萄糖转运体)

Glucose transporter

GLUT(葡萄糖转运蛋白)是由 12 个跨膜区域组成的蛋白质。GLUT 通过促进扩散机制将葡萄糖转运到质膜上。

GLUT1(SLC2A1)是一种单向转运蛋白,可促进葡萄糖转运到哺乳动物细胞的质膜上。GLUT2(SLC2A2)是一种跨膜载体蛋白,可使蛋白质促进葡萄糖跨细胞膜移动。GLUT3(SLC2A3)主要存在于大脑中,对葡萄糖具有很高的亲和力。GLUT3 促进葡萄糖跨哺乳动物细胞的质膜转运。GLUT4(SLC2A4)存在于心脏、骨骼肌、脂肪组织和大脑中。GLUT4 是一种胰岛素反应性葡萄糖转运蛋白。

GLUTs (Glucose transporters ) are proteins comprising 12 membrane-spanning regions. GLUTs transport glucose across the plasma membrane by means of a facilitated diffusion mechanism.

GLUT1 (SLC2A1), a uniporter protein, facilitates the transport of glucose across the plasma membranes of mammalian cells. GLUT2 (SLC2A2) is a transmembrane carrier protein that enables protein facilitated glucose movement across cell membranes. GLUT3 (SLC2A3), mainly present in the brain, has high affinity for glucose. GLUT3 facilitates the transport of glucose across the plasma membranes of mammalian cells. GLUT4 (SLC2A4) is found in the heart, skeletal muscle, adipose tissue, and brain. GLUT4 is an insulin-responsive glucose transporter.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-167857
    (Rac)-Glutipyran Inhibitor
    (Rac)-Glutipyran 是一种广谱 GLUT 抑制剂,同时靶向 GLUT1GLUT3。(Rac)-Glutipyran 抑制葡萄糖摄取并抑制多种癌细胞的生长,显著抑制 PANC-1 细胞生长 (IC50=1.8 μM) 和葡萄糖摄取 (IC50=0.13 μM)。
    (Rac)-Glutipyran
  • HY-W411439
    1-O-p-Coumaroyl-β-D-glucose Inhibitor
    1-O-p-Coumaroyl-β-D-glucose 可促进 HuH7 细胞对葡萄糖的摄取,可以从丝瓜中提取。
    1-O-p-Coumaroyl-β-D-glucose
  • HY-N6935R
    Sennidin B (Standard) Activator
    Sennidin B (Standard) 是 Sennidin B 的分析标准品。本产品用于研究及分析应用。Sennidin B可从Cassia angustifolia 分离得到,是Sennidin A 的异构体,活性比Sennidin A 低。Sennidin A,能够抑制HCV NS3 解旋酶,其 IC50 值为0.8 μM。Sennidin A诱导Akt和葡萄糖转运蛋白4 (GLUT4) 的磷酸化。Sennidin A刺激葡萄糖掺入。
    Sennidin B (Standard)
目录号 产品名 / 同用名 应用 反应物种

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.