2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. A-278637

A-278637 是一种选择性 KATP 通道开放剂，EC50 值为 102 nM。A-278637 不与其他离子通道 (包括 L 型钙通道) 或其他神经递质受体系统相互作用。A-278637 在体内对膀胱的功能选择性高于血管平滑肌。A-278637 可用于研究膀胱过度活动症。

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A-278637

A-278637 Chemical Structure

CAS No. : 227609-66-7

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A-278637 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

A-278637 is a selective KATP channel opening agent with an EC50 of 102 nM. A-278637 does not interact with other ion channels, including L-type calcium channels or other neurotransmitter receptor systems. A-278637 possesses a greater functional selectivity for urinary bladder versus vascular smooth muscle in vivo. A-278637 can be used for the study of overactive bladder[1][2].

分子量

412.27

Formula

C17H15BrFNO3S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

A-278637 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

A-278637227609-66-7A278637A 278637Potassium ChannelKcsAKATP channel openingoveractive bladderInhibitorinhibitorinhibit

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产品名称：
A-278637
目录号：
HY-138983
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