2. Cell Cycle/DNA Damage Stem Cell/Wnt PROTAC
  3. Casein Kinase PROTACs
  4. AH081

AH081 (Compound 38) 是一种 CK1δ/ε PROTAC 降解剂。AH081 是 AH078 (HY-170859) 的阴性对照物。AH081 通过使用 VHL 配体的无活性立体异构体，使其对 CK1δ/ε 具有抑制活性但没有降解活性。粉色：CK1δ/ε ligand (HY-148251)；蓝色：VHL ligase ligand (HY-125845B)；黑色：linker

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AH081

AH081 Chemical Structure

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

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规格 是否有货
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Customer Review

Other Forms of AH081:

AH081 相关抗体

Top Publications Citing Use of Products

查看 Casein Kinase 亚型特异性产品:

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CK1 CK2

查看 PROTACs 亚型特异性产品:

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AH081 (Compound 38) is a CK1δ/ε PROTAC degrader. AH081 is the negative control compound of AH078 (HY-170859). AH081 has inhibitory but no degradation activity for CK1δ/ε by using an inactive stereoisomer of the VHL ligand[1]. Pink: CK1δ/ε ligand (HY-148251); Blue: VHL ligase ligand (HY-125845B); Black: linker

IC50 & Target[1]

CK1δ

 

CK1ε

 

分子量

963.15

Formula

C51H60F2N10O5S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AH081 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AH081AH 081AH-081Casein KinasePROTACsPROTACCK1δ/εInhibitoryNegative controlAH078Inhibitorinhibitorinhibit

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产品名称：
AH081
目录号：
HY-170859A
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