2. Neuronal Signaling
  3. α-synuclein
  4. α-Synuclein-IN-18

α-Synuclein-IN-18 (Compound Mol D) 是一种 α-突触核蛋白 (α-Synuclein) 聚集体自催化增殖的抑制剂。α-Synuclein-IN-18 能特异性结合到 α-突触核蛋白原纤维表面的保守结合口袋上。α-Synuclein-IN-18 可延缓 α-突触核蛋白的聚集过程，将聚集 T1/2 延长三倍。α-Synuclein-IN-18 能减少 α-突触核蛋白毒性寡聚体的生成量，从而减轻神经毒性。α-Synuclein-IN-18 可用于帕金森病的研究。

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α-Synuclein-IN-18

α-Synuclein-IN-18 Chemical Structure

CAS No. : 1394328-54-1

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α-Synuclein-IN-18 相关抗体

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查看 α-synuclein 亚型特异性产品:

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α-synuclein α-synuclein Aggregation α-synuclein/CHMP2B

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生物活性

α-Synuclein-IN-18 (Compound Mol D) is an inhibitor of the autocatalytic proliferation of α-Synuclein aggregate. α-Synuclein-IN-18 can specifically bind to the conserved binding pocket on the surface of α-synuclein fibrils. α-Synuclein-IN-18 can delay the aggregation process of α-synuclein, extend the aggregation T1/2 by three times. α-Synuclein-IN-18 can reduce the generation flux of α-synuclein toxic oligomers, thereby alleviating the neurotoxicity. α-Synuclein-IN-18 can be used for research of Parkinson’sdisease[1].

分子量

296.32

Formula

C16H16N4O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
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α-Synuclein-IN-18 相关分类

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Keywords:

α-Synuclein-IN-181394328-54-1α-synucleinα-SynInhibitorinhibitorinhibit

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