Aluminum hydroxide adjuvant 

Aluminum hydroxide adjuvant is a vaccine adjuvant. The aluminum content is 9-11 mg/mL. Aluminum hydroxide adjuvant induces the differentiation of macrophages into a new type of mature, specialized antigen-presenting cells in vitro^[1]. It has a strong adsorption capacity for negatively charged antigens, a significant sustained-release effect, no stress response, high safety, and can effectively induce immune responses in the body. It is suitable for various veterinary vaccines, including inactivated vaccines or gene-engineered subunit vaccines for bacterial and viral diseases of livestock and poultry. It is suitable for various veterinary vaccines, including inactivated vaccines or gene-engineered subunit vaccines for bacterial and viral diseases of livestock and poultry.

推荐在将抗原与佐剂混合之前对其进行除菌过滤。

1. 使用前将佐剂摇晃均匀。

2. 按照 1:9 （每 900 μL 抗原加入 100 μL佐剂）的比例将佐剂与抗原充分混合：

a. 向抗原溶液中逐滴加入佐剂，并持续搅拌。

b. 反复上下吹打多次，确保抗原被佐剂充分吸收，并孵育 10 分钟。

注意：具体比例请根据自身实验条件（如实验目的等）进行摸索和优化。比例可以从 1:1 调整到 1:9 。

3. 给动物注射，注射量取决于注射部位。

注意：开封后的产品需要在2-8℃冷藏保存，开封后需在3个月内尽快用完，避免高温高压和反复冻融。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

液体

White to off-white

Room temperature in continental US; may vary elsewhere.

Store at 4°C, do not freeze

• [1]. Rimaniol AC, et al. Aluminum hydroxide adjuvant induces macrophage differentiation towards a specialized antigen-presenting cell type. Vaccine. 2004 Aug 13;22(23-24):3127-35.  [Content Brief]