2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. TRP Channel
  4. AM-0883

AM-0883 是一种 TRPC6 (瞬时受体电位经典 6) 激动剂 (hTRPC6 EC50 = 46 nM)。AM-0083 可用于心脏和肾脏疾病的研究。

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AM-0883

AM-0883 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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Customer Review

AM-0883 相关抗体

Top Publications Citing Use of Products

查看 TRP Channel 亚型特异性产品:

查看所有亚型
TRPA1 TRPC3 TRPC4 TRPC5 TRPM8 TRPM2 TRPM3 TRPM4 TRPML1 TRPML2 TRPML3 TRPV1 TRPV2 TRPV3 TRPV4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AM-0883 is a TRPC6 (Transient receptor potential canonical 6) agonist (hTRPC6 EC50 = 46 nM). AM-0083 can be used for the study of cardiac and renal diseases[1][2].

IC50 & Target

hTRPC6

46 nM (EC50)

体外研究
(In Vitro)

AM-0883 可激活 HEK293T 细胞中的野生型 TRPC6 (EC50 = 45.5 nM) 和 HEK293T N 端截短突变体 TRPC6 (Δ2–72) (EC50 = 90.2 nM)[1]。
AM-0883 通过 S6/孔道螺旋连接处的特定残基激活该通道[1]。
AM-0883 对 V867T/L868T 双突变体的激活作用显著强于对野生型通道的激活作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

AM-0883 相关抗体:
分子量

384.86

Formula

C21H21ClN2O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AM-0883 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AM-0883AM0883AM 0883TRP ChannelTransient receptor potential channelsTRPC6 agonistTRPC6 channel activationInhibitorinhibitorinhibit

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产品名称：
AM-0883
目录号：
HY-179490
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