2. Anti-infection
  3. HIV
  4. anti-HIV agent 1

Antiviral agent 72 (compound 10i) 是一种强效抗病毒 (antiviral) 剂，具有抗 HIV 活性 (IC50 = 10.6 nM)。Antiviral agent 72 对 RT 突变株的抑制活性中等或无抑制活性，但对野生型病毒仍保持活性。Antiviral agent 72 对病毒生命周期的病毒附着和逆转录酶阶段均表现出显著的双重抑制作用。Antiviral agent 72 可用于 HIV 感染研究。

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anti-HIV agent 1

anti-HIV agent 1 Chemical Structure

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anti-HIV agent 1 相关抗体

Top Publications Citing Use of Products

查看 HIV 亚型特异性产品:

查看所有亚型
HIV HIV-1 HIV-2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antiviral agent 72 (compound 10i) is a potent antiviral agent with anti-HIV activity (IC50 = 10.6 nM). Antiviral agent 72 exhibits moderate to no inhibitory activity against RT mutant strains, but maintained their activity against wild-type viruses. Antiviral agent 72 strongly shows dual inhibition of the viral attachment and reverse transcriptase phases of the viral life cycle. Antiviral agent 72 can be used for HIV infection research[1].

IC50 & Target[1]

HIV-1

10.6 nM (IC50)

分子量

455.38

Formula

C23H24Cl2N6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

anti-HIV agent 1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

anti-HIV agent 1HIVHuman immunodeficiency virusantiviralviral attachmentreverse transcriptaseinfectionInhibitorinhibitorinhibit

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