1. Anti-infection
  2. Bacterial
  3. Antibacterial agent 298

Antibacterial agent 298 对恶臭假单胞菌 (ATCC 25922) 表现出显著的抗菌活性,IC50 值为 4.48 µg/mL。Antibacterial agent 298 具有很强的抗生物膜活性。此外,Antibacterial agent 298 还能抑制乳酸乳球菌和恶臭假单胞菌约 50 % 的生物膜形成。Antibacterial agent 298 可用于研究由多重耐药菌 (MDR) 引起的细菌感染。

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Antibacterial agent 298

Antibacterial agent 298 Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antibacterial agent 298 exhibits significant antibacterial activity against Pseudomonas putida (ATCC 25922) with an IC50 4.48 µg/mL. Antibacterial agent 298 shows strong antibiofilm activity. Antibacterial agent 298 also inhibits approximately 50% of biofilm formation in L. lactis and P. putida. Antibacterial agent 298 can be used for the study of Bacterial infections caused by multidrug-resistant bacteria (MDR)[1].

体外研究
(In Vitro)

Antibacterial agent 298 (Compound 3a) (10-100 μg/mL,24 小时) 对革兰氏阳性菌和革兰氏阴性菌均表现出良好的抗菌效果,尤其对革兰氏阴性菌的抗菌效果显著[1]
Antibacterial agent 298 对所有测试菌株均表现出浓度依赖性的抗生物膜活性:乳酸乳球菌 (MIC50 = 24.8 μg/mL);巨大芽孢杆菌 (MIC50 = 48.6 μg/mL);恶臭假单胞菌 (MIC50 = 28.3 μg/mL);以及粘质沙雷氏菌 (MIC50 = 31.9 μg/mL)[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: Pseudomonas putida (ATCC25922), Bacillus megaterium (QMB1551), Lactococcus Lactis (NZ900), Marcescens Serratia (NCTC10211)
Concentration: 10 μg/mL, 20 μg/mL, 30 μg/mL, 40 μg/mL, 50 μg/mL, 60 μg/mL, 70 μg/mL, 80 μg/mL, 90 μg/mL, 100 μg/mL
Incubation Time: 24 h
Result: Lactococcus Lactis (NZ900) (IC50 = 9.48 μg/mL)
Bacillus Megaterium (QMB1551) (IC50 = 7.02 μg/mL)
Pseudomonas putida (ATCC25922) (IC50 = 4.48 μg/mL)
Marcescens Serratia (NCTC10211) (IC50 = 17.26 μg/mL)
分子量

742.94

Formula

C45H58O9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Antibacterial agent 298 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Antibacterial agent 298
目录号:
HY-178924
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