1. Anti-infection Immunology/Inflammation
  2. Enterovirus IFNAR
  3. Antiviral agent 79

Antiviral agent 79 是一种广谱抗病毒剂。Antiviral agent 79 具有抗 EV71、抗 CVB3 和抗 ADV7 活性。Antiviral agent 79 可激活宿主 I 型干扰素信号通路以增强抗病毒防御。Antiviral agent 79 可用于病毒感染的相关研究。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Antiviral agent 79

Antiviral agent 79 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antiviral agent 79 is a broad-spectrum antiviral agent. Antiviral agent 79 exhibits anti-EV71, anti-CVB3 and anti-ADV7 activities. Antiviral agent 79 activates the host type I interferon signaling pathway to enhance antiviral defense. Antiviral agent 79 can be used in research related to viral infections[1].

体外研究
(In Vitro)

Antiviral agent 79 (compound 8d) (0-100 μM; 48 h) 可强效抑制 Vero 细胞中 EV71 的复制,其 EC50 为 12.86 μM,CC50 为 175.1 μM,并且可呈浓度依赖性地降低病毒子代的产生及 GFP 阳性感染细胞的数量[1]
Antiviral agent 79 (0-100 μM; 48 h) 可抑制 Hep-2 细胞中 CVB3 的复制,其 EC50 为 19.58 μM,CC50 为 156.6 μM,SI 为 7.99;且在高浓度下可阻断病毒诱导的细胞病变效应[1]
Antiviral agent 79 (48 h) 可抑制 HeLa 细胞中 ADV7 的复制,其 EC50 为 10.29 μM,CC50 为 145.8 μM;且在 50 μM 浓度下可阻断病毒诱导的细胞病变效应[1]
Antiviral agent 79 (100 μM; 4-32 h) 可通过抑制病毒 RNA 合成与蛋白质翻译来阻断 Vero 细胞中 EV71 的复制[1]
Antiviral agent 79 (50 μM; 32 h) 可显著上调 IFN-β mRNA 的表达,激活 RD 细胞中的宿主 I 型干扰素通路[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Real Time qPCR[1]

Cell Line: RD cells
Concentration: 50 μM
Incubation Time: 16, 32 h
Result: Significantly upregulated IFN-β mRNA levels at 32 h post-treatment.
分子量

538.04

Formula

C27H32ClN7O3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Antiviral agent 79
目录号:
HY-181603
需求量: