2. Metabolic Enzyme/Protease
  3. E1/E2/E3 Enzyme
  4. Apazunersen

Apazunersen 是一种反义寡核苷酸，能够靶向并抑制 UBE3A 反义转录本 (UBE3A-AS) 的表达，从而防止 UBE3A 基因中父系遗传等位基因的沉默，并重新激活缺陷蛋白质的表达，被用于研究天使综合征。

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DNA, d(P-thio)((2'-O,4'-C-methylene)rA-(2'-O,4'-C-methylene)rG-(2'-O,4'-C-methylene)rA-A-T-G-G-C-A-C-A-T-C-T-(2'-O,4'-C-methylene)m5rC-(2'-O,4'-C-methylene)m5rU-(2'-O,4'-C-methylene)m5rU-(2'-O,4'-C-methylene)rG)

Apazunersen Chemical Structure

CAS No. : 2919324-01-7

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Apazunersen 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Apazunersen is an antisense oligonucleotide (ASO) that targets and inhibits expression of the UBE3A antisense transcript (UBE3A-AS) to prevent silencing of the paternally inherited allele of the UBE3A gene and reactivate expression of the deficient protei

分子量

5981.79

Formula

C184H224N67O96P17S17
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Apazunersen 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Apazunersen2919324-01-7GTX-102GTX102GTX 102E1/E2/E3 EnzymeE1 activating enzymeE2 conjugating enzymeE3 ligating enzymeUbiquitin activating enzymeUbiquitin conjugating enzymeUbiquitin ligaseInhibitorinhibitorinhibit

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产品名称：
Apazunersen
目录号：
HY-177615
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