2. Anti-infection
  3. HIV Reverse Transcriptase
  4. Atevirdine mesylate

Atevirdine (U 87201E) mesylate 是一种非核苷类逆转录酶 (NNRT) 抑制剂。Atevirdine mesylate 能够抑制 1 型人类免疫缺陷病毒 (HIV-1)，其 IC50 值为 0.06-1.6 μM。Atevirdine mesylate 与 Zidovudine (HY-17413)/Didanosine (Hy-B0249) 联合使用时，对 Zidovudine/Didanosine 耐药的 HIV-1 临床分离株表现出高度的协同作用。Atevirdine mesylate 可用于艾滋病的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Atevirdine mesylate

Atevirdine mesylate Chemical Structure

CAS No. : 138540-32-6

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

Atevirdine mesylate 相关抗体

Top Publications Citing Use of Products

查看 HIV 亚型特异性产品:

查看所有亚型
HIV HIV-1 HIV-2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Atevirdine (U 87201E) mesylate is a nonnucleoside reverse transcriptase (NNRT) inhibitor. Atevirdine mesylate can inhibit human immunodeficiency virus type 1 (HIV-1) with an IC50 of 0.06-1.6 μM. Atevirdine mesylate shows highly synergistic effects against Zidovudine/Didanosine-resistant clinical isolates of HIV-1 companied with Zidovudine (HY-17413)/Didanosine (Hy-B0249). Atevirdine mesylate can be used for the research of AIDS[1].

IC50 & Target[1]

HIV-1

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
MT2 CC50
> 20 μM
Compound: 80
Tested for the drug concentration required to decrease HIV-1IIIb infected MT-2 cell viability compared to uninfected controls
Tested for the drug concentration required to decrease HIV-1IIIb infected MT-2 cell viability compared to uninfected controls
[PMID: 7512142]
MT2 ED50
< 0.2 μM
Compound: 80
Effective antiviral dose required to block the spread of HIV-1 IIIb infection in MT-2 cells by monitoring the formation of syncytia
Effective antiviral dose required to block the spread of HIV-1 IIIb infection in MT-2 cells by monitoring the formation of syncytia
[PMID: 7512142]
分子量

475.56

Formula

C22H29N5O5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Atevirdine mesylate 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Atevirdine138540-32-6U 87201EHIVReverse TranscriptaseHuman immunodeficiency virusInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Atevirdine mesylate
目录号：
HY-105097
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z