2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. AZ12441970

AZ12441970 是一种强效且选择性的 Toll 样受体 7 (TLR7) 激动剂，对人 TLR7 和大鼠 TLR7 的 pEC50 值分别为 6.8 和 6.6。AZ12441970 在小鼠过敏性气道模型中显示出功效，且仅诱导极轻微的系统性 IFN-α。AZ12441970 可用于过敏性气道疾病的研究。

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AZ12441970

AZ12441970 Chemical Structure

CAS No. : 929551-91-7

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AZ12441970 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AZ12441970 is a potent and selectiveToll-like receptor 7 (TLR7) agonist, exhibiting pEC50s of 6.8 and 6.6 for human and rat TLR7. AZ12441970 shows efficacy in a mouse allergic airway model with minimal induction of systemic IFN-α. AZ12441970 can be used for allergic airway disease research[1].

IC50 & Target[1]

human TLR7

6.8 (pEC50)

Rat TLR7

6.6 (pEC50)

分子量

527.66

Formula

C27H41N7O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AZ12441970 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AZ12441970929551-91-7AZ 12441970AZ-12441970Toll-like Receptor (TLR)TLR7mouse allergic airway modelsystemic IFN-αInhibitorinhibitorinhibit

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产品名称：
AZ12441970
目录号：
HY-117686
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