2. Immunology/Inflammation
  3. PD-1/PD-L1
  4. BMS-103

BMS-103 是一种 PDL1 抑制剂 (IC50 = 79.1 nM) (kd = 44 nM)。BMS-103 降低急性 T 淋巴细胞白血病细胞和卵巢细胞存活率。BMS-103 可用于急性 T 淋巴细胞白血病和卵巢癌等癌症的研究。

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BMS-103

BMS-103 Chemical Structure

CAS No. : 1675202-86-4

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BMS-103 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BMS-103 is a PDL1 inhibitor (IC50 = 79.1 nM) (kd = 44 nM). BMS-103 reduces the survival rate of acute T-lymphoblastic leukemia cells and ovarian cells. BMS-103 can be used in research on acute T-lymphoblastic leukemia and cancers such as ovarian cancer[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Jurkat IC50
5.7 μM
Compound: A1
Cytotoxicity against human Jurkat cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
Cytotoxicity against human Jurkat cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
[PMID: 37226718]
分子量

407.50

Formula

C25H29NO4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BMS-103 相关分类

  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BMS-1031675202-86-4BMS103BMS 103PD-1/PD-L1PD-1/Programmed death-ligand 1Inhibitorinhibitorinhibit

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目录号：
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