2. Anti-infection Metabolic Enzyme/Protease
  3. HCV Protease
  4. BMS 605339

BMS 605339 是一种线性四肽 α-酮酰胺 HCV NS3 蛋白酶抑制剂。BMS 605339 可用于丙型肝炎 (HCV 感染) 相关研究。

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BMS 605339

BMS 605339 Chemical Structure

CAS No. : 630417-82-2

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BMS 605339 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BMS 605339 is a linear tetra-peptide α-ketoamide inhibitor of HCV NS3 protease. BMS 605339 can be used in research related to hepatitis C (HCV infection)[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Huh-7 CC50
> 100 μM
Compound: 35, BMS-605339
Cytotoxicity against human HuH7 cells
Cytotoxicity against human HuH7 cells
[PMID: 24555570]
Huh-7 EC50
12 nM
Compound: 1; BMS-605339
Antiviral activity against HCV genotype 1b Con1 expressing NS3 protease infected in human Huh7.5 cells assessed as reduction in viral RNA replication by luciferase reporter gene assay
Antiviral activity against HCV genotype 1b Con1 expressing NS3 protease infected in human Huh7.5 cells assessed as reduction in viral RNA replication by luciferase reporter gene assay
[PMID: 27564532]
分子量

713.84

Formula

C35H47N5O9S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BMS 605339 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BMS 605339630417-82-2BMS605339BMS-605339HCV ProteaseHCV NS3 ProteaseinfectionInhibitorinhibitorinhibit

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