2. Membrane Transporter/Ion Channel Neuronal Signaling Stem Cell/Wnt
  3. Calcium Channel Notch
  4. CAD204520 dihydrochloride

CAD204520 dihydrochloride 

目录号: HY-164466A 纯度: 99.26%
COA 产品使用指南 技术支持

CAD204520 dihydrochloride 是一种 SERCA 的抑制剂 (IC50 = 0.34 μM)，靶向 T 细胞急性淋巴细胞白血病 (T-ALL) 和套细胞淋巴瘤 (MCL) 中突变型 NOTCH1 蛋白。CAD204520 dihydrochloride 可用于 T-ALL 和 MCL 相关研究。

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CAD204520 dihydrochloride

CAD204520 dihydrochloride Chemical Structure

CAS No. : 2682205-21-4

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规格 价格 是否有货 数量
5 mg ￥2890
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10 mg ￥4675
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Other Forms of CAD204520 dihydrochloride:

CAD204520 dihydrochloride 相关抗体

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CAD204520 dihydrochloride, a SERCA inhibitor (IC50 = 0.34 μM), targets mutated over wild type NOTCH1 proteins in T-cell acute lymphoblastic leukemia (T-ALL) and mantle cell lymphoma (MCL). CAD204520 dihydrochloride can be used for T-ALL and MCL research[1].

IC50 & Target[1]

SERCA

0.34 μM (IC50)

NOTCH1

 

分子量

512.44

Formula

C23H34Cl2F3N3O2
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

纯度 & 产品资料
参考文献

CAD204520 dihydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CAD2045202682205-21-4CAD 204520CAD-204520Calcium ChannelNotchCa2+ channelsCa channelsSERCAT-ALLMCLNOTCH1Inhibitorinhibitorinhibit

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