2. Metabolic Enzyme/Protease Anti-infection Others
  3. Carbonic Anhydrase Bacterial Drug Derivative
  4. CAI0019

CAI0019 是一种口服有效的、基于 Acetazolamide (HY-B0782) 骨架的 α-碳酸酐酶 (α-carbonic anhydrase) 抑制剂。CAI0019 具有窄谱抗肠球菌活性，其 MIC50 为 0.094 μM，MIC90 为 0.39 μM。CAI0019 在败血性腹膜炎小鼠模型选择性抑制肠球菌，对大多数肠道共生菌没有影响。

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CAI0019

CAI0019 Chemical Structure

CAS No. : 2446169-48-6

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规格 价格 是否有货
5 mg ￥824
询问价格 & 货期
10 mg ￥1318
询问价格 & 货期
25 mg ￥2592
询问价格 & 货期
50 mg ￥4148
询问价格 & 货期
100 mg 询价 询问价格 & 货期

* Please select Quantity before adding items.

Customer Review

CAI0019 相关抗体

Top Publications Citing Use of Products

查看 Carbonic Anhydrase 亚型特异性产品:

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CA CA I CA Ⅱ CA IX CA XII

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CAI0019 is an orally active α-carbonic anhydrase inhibitor based on the Acetazolamide (HY-B0782) framework. CAI0019 exhibits narrow-spectrum antibiofilm activity, with its MIC50 being 0.094 μM and MIC90 being 0.39 μM. CAI0019 selectively inhibits Enterococcus in a septic peritonitis mouse model, without affecting most intestinal commensal bacteria[1].

分子量

318.42

Formula

C11H18N4O3S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CAI0019 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CAI00192446169-48-6CAI 0019CAI-0019Carbonic AnhydraseBacterialDrug DerivativeCarbonate dehydrataseDrug derivativeCarbonic anhydrase inhibitorNarrow-spectrum antibioticVancomycin-resistant EnterococciMicrobiome preservationChemoproteomicsPharmacokineticsAnimal efficacy modelBacterial metabolism targetingInhibitorinhibitorinhibit

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产品名称：
CAI0019
目录号：
HY-180542
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