2. Others
  3. Fluorescent Dye
  4. CAQ

CAQ 是一种基于姜黄素支架的近红外荧光探针 (Ex/Em = 565/635)。CAQ 与 Aβ1-42 聚集体表现出高亲和力 (Kd = 78.89 nM)，对常见生物分子表现出优异的选择性。CAQ 的发射波长显示明显的溶剂依赖性。CAQ 通过引入分子内旋转供体和喹啉功能基团，可用于阿尔茨海默病中 Aβ 聚集体的特异性检测和成像。

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CAQ

CAQ Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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Customer Review

CAQ 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CAQ is a near-infrared fluorescent probe based on a curcumin scaffold (Ex/Em = 565/635). CAQ exhibits high affinity for Aβ1-42 aggregates (Kd = 78.89 nM) and excellent selectivity toward common biomolecules. CAQ’s emission wavelength shows significant solvent dependence. CAQ, by incorporating intramolecular rotation donors and quinoline functional groups, can be used for the specific detection and imaging of Aβ aggregates in Alzheimer's disease[1].
分子量

418.24

Formula

C24H21BF2N2O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CAQ 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CAQFluorescent Dyeamyloid-β plaquesnear-infrared probebrain imagingin vivoAlzheimer's diseasefluorescence imagingmolecular probeAβ aggregatesdiagnostic imagingneurodegenerative diseaseInhibitorinhibitorinhibit

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