2. Anti-infection
  3. Bacterial
  4. cCBD-LL37

cCBD-LL37 是一种经胶原结合域 (cCBD) (TKKTLRT) 修饰的嵌合抗菌肽。cCBD-LL37 在 PBS 洗涤和不同静电条件下均能更好地保留在胶原蛋白上。cCBD-LL37 与胶原蛋白的结合涉及特异性和非特异性相互作用，由长程静电力引发，随后转变为近程或疏水相互作用。cCBD-LL37 具有强效抗菌活性，并在不同的离子强度和 pH 条件 (pH 5.5-8) 均具有稳定结构稳定。cCBD-LL37 可用于胶原蛋白基伤口敷料等生物材料研究。

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Custom Peptide Synthesis

cCBD-LL37

cCBD-LL37 Chemical Structure

CAS No. : 2378579-44-1

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cCBD-LL37 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

cCBD-LL37 is a chimeric antimicrobial peptide modified with a collagen-binding domain (cCBD) (TKKTLRT). cCBD-LL37 has improved retention on collagen after PBS washing and varying electrostatic conditions. cCBD-LL37 binds to collagen involves both specific and non-specific interactions, initiated by long-range electrostatic forces that transitions to close range or hydrophobic interactions. cCBD-LL37 has potent antimicrobial activity with improved structural stability under different ionic strengths and pH conditions (pH 5.5-8). cCBD-LL37 can be used for biomaterials like collagen-based wound dressings research[1].

分子量

6317.22

Formula

C282H466N82O82
CAS 号
Sequence

Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys-Thr-Lys-Lys-Thr-Leu-Arg-Thr
Sequence Shortening

LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTESDYKDDDDKTKKTLRT
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

cCBD-LL37 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

cCBD-LL372378579-44-1BacterialChimeric antimicrobial peptidecCBDAntimicrobialWound dressingsInhibitorinhibitorinhibit

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