1. Metabolic Enzyme/Protease
  2. Phosphatase
  3. CDC25B-IN-1

CDC25B-IN-1 (compound 4a) 是一种有效的细胞分裂周期 25B (CDC25B) 磷酸酶抑制剂,其 Ki 值为 8.5 μM。CDC25B-IN-1 能有效抑制细胞增殖和克隆形成,导致 G2/M 期停滞。

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CDC25B-IN-1

CDC25B-IN-1 Chemical Structure

CAS No. : 2374831-10-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CDC25B-IN-1 (compound 4a) is a potent inhibitor of cell division cycle 25B (CDC25B) phosphatase, with a Ki of 8.5 μM. CDC25B-IN-1 potently inhibits cell proliferation and colony formation, causes an increase of the G2/M phase[1].

IC50 & Target

Ki: 8.5 μM (CDC25B phosphatase)[1]

分子量

321.37

Formula

C20H19NO3

CAS 号
性状

油状物

颜色

Light brown to brown

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

纯度 & 产品资料
参考文献
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
CDC25B-IN-1
目录号:
HY-126246
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