1. GPCR/G Protein Neuronal Signaling Immunology/Inflammation Anti-infection
  2. Histamine Receptor SARS-CoV Filovirus Parasite
  3. Chlorphenoxamine hydrochloride

Chlorphenoxamine hydrochloride 是一种抗组胺剂和抗胆碱能剂,也是 GPCR 拮抗剂。Chlorphenoxamine hydrochloride 可抑制多种致命病毒性疾病,例如 SARS-CoVMERS-CoV、埃博拉病毒 (EBOV) 和疟疾。Chlorphenoxamine hydrochloride 对 EBOV 和马尔堡病毒 (MARV) 均具有抗丝状病毒活性,其 IC50 分别为 1.1 μM 和 6.2 μM。Chlorphenoxamine hydrochloride 用于研究过敏性疾病、荨麻疹、病毒性疾病和帕金森病。

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Chlorphenoxamine hydrochloride

Chlorphenoxamine hydrochloride Chemical Structure

CAS No. : 562-09-4

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Chlorphenoxamine hydrochloride 的其他形式现货产品:

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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Chlorphenoxamine hydrochloride, an antihistamine and anticholinergic agent is a GPCR antagonist. Chlorphenoxamine hydrochloride inhibits multiple lethal viral diseases, such as SARS-CoV, MERS-CoV, EBOV and malaria. Chlorphenoxamine hydrochloride shows anti-filovirus activity against both EBOV and Marburg virus (MARV) with IC50s of 1.1 μM and 6.2 μM, respectively. Chlorphenoxamine hydrochloride is used for allergic conditions, urticaria, viral diseases and Parkinson’s disease[1][2][3][4][5].

分子量

340.29

Formula

C18H23Cl2NO

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Chlorphenoxamine hydrochloride
目录号:
HY-B1607A
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