2. Metabolic Enzyme/Protease Others
  3. Acetyl-CoA Carboxylase Drug Derivative
  4. CKBA

CKBA，AKBA (HY-N0892) 的衍生物，是一种乙酰辅酶 A 羧化酶 1 (ACC1) 抑制剂，其 IC50 为 5.02 μM。CKBA 抑制 Th17 细胞分化，对小鼠和人类细胞的 IC50 分别为 3.28 μM 和 3.61 μM。CKBA 软膏显著缓解小鼠银屑病样炎症。CKBA 可用于研究银屑病。

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CKBA

CKBA Chemical Structure

CAS No. : 1786406-66-3

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规格 价格 是否有货 数量
5 mg ￥3500
3 - 4 周
10 mg ￥5300
3 - 4 周
25 mg 询价 3 - 4 周
50 mg 询价 3 - 4 周
100 mg 询价 3 - 4 周
200 mg   询价  
500 mg   询价  

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Customer Review

CKBA 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CKBA, a derivative of AKBA (HY-N0892) is an inhibitor of acetyl-CoA carboxylase 1 (ACC1), with an IC50 of 5.02 μM. CKBA inhibits the differentiation of Th17 cells and has IC50 values of 3.28 μM for mouse cells and 3.61 μM for human cells. CKBA ointment significantly alleviates psoriasis-like inflammation in mice. CKBA can be used for the study of psoriasis[1].

分子量

580.84

Formula

C37H56O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CKBA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CKBA1786406-66-3Acetyl-CoA CarboxylaseDrug DerivativeACC, Acetyl Coenzyme A Carboxylase Drug derivativeAKBAefficacy and safety profilepsoriasistopical drugInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-179537
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