1. Metabolic Enzyme/Protease
  2. RPE65
  3. CU239

CU239 是一种强效的、竞争性的 RPE65 的非维甲酸抑制剂,其对 RPE65 异构酶 (11-顺式视黄醇) 的 IC50 为 6 μM。CU239 抑制视觉周期,延迟视觉色素再生,并保护视网膜免受光诱导损伤。CU239 可用于研究视网膜变性。

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CU239

CU239 Chemical Structure

CAS No. : 946249-82-7

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  • 生物活性

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生物活性

CU239 is a potent and competitive non-retinoic acid inhibitor of RPE65 with an IC50 for RPE65 isomerase (11-cis retinal) of 6 μM. CCU239 exhibits delayed chromophore regeneration after light bleach, and conferrs a partial protection of the retina against injury from high intensity light. CU239 can be used for the study of retinal degeneration[1].

分子量

436.41

Formula

C19H15F3N4O3S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
CU239
目录号:
HY-119059
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