2. Metabolic Enzyme/Protease
  3. Cytochrome P450
  4. CYP17A1-IN-2

CYP17A1-IN-2 是一种 CYP17A1 抑制剂。CYP17A1-IN-2 对前列腺癌细胞具有抗增殖活性。CYP17A1-IN-2 可用于去势抵抗性前列腺癌的相关研究。

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CYP17A1-IN-2

CYP17A1-IN-2 Chemical Structure

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CYP17A1-IN-2 相关抗体

Top Publications Citing Use of Products

查看 Cytochrome P450 亚型特异性产品:

查看所有亚型
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CYP17A1-IN-2 is a potent inhibitor of CYP17A1. CYP17A1-IN-2 exhibits anti-proliferative activity against prostate cancer cells. CYP17A1-IN-2 can be used in research related to castration-resistant prostate cancer[1].

IC50 & Target[1]

CYP17A1

 

体外研究
(In Vitro)

CYP17A1-IN-2 (Compound 14c) 可强效抑制 PC-3 和 LNCaP 前列腺癌细胞的增殖，其 GI50 值分别为 8.9 ± 2.2 nM 和 30.5 ± 3.1 nM[1]。
CYP17A1-IN-2 hydrochloride salt 在 pH 7.0 PBS 中的溶解度为 0.173 mg/mL[1]。
CYP17A1-IN-2 (250 nM) 在小鼠睾丸匀浆中对 CYP17A1 的抑制率为 31 ± 16%[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CYP17A1-IN-2 相关抗体:
分子量

359.42

Formula

C23H21NO3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CYP17A1-IN-2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CYP17A1-IN-2Cytochrome P450CYPsLNCaPPC-3castration-resistant prostate cancerCYP17A1mouse testicular homogenateprostate cancer cellsInhibitorinhibitorinhibit

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目录号：
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