1. Anti-infection
  2. Fungal
  3. D-Cateslytin

D-Cateslytin 是一种抗菌肽,对白色念珠菌具有强效抑菌活性 (MIC = 2.9 μM)。D-Cateslytin 能快速进入白色念珠菌细胞,对人牙龈成纤维细胞无细胞毒性,且在唾液中保持稳定。D-Cateslytin 可用于研究白色念珠菌相关疾病,例如口腔念珠菌病的研究。

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Custom Peptide Synthesis

D-Cateslytin

D-Cateslytin Chemical Structure

CAS No. : 3002053-77-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

D-Cateslytin is an antimicrobial peptide that exhibits potent inhibition activity against Candida albicans (MIC = 2.9 μM). D-Cateslytin can rapidly enter C. albicans, shows no cytotoxicity to human gingival fibroblasts, and is stable in saliva. D-Cateslytin can be used for research on Candida albicans related diseases, such as oral candidosis[1].

体外研究
(In Vitro)

D-Cateslytin (0-100 μg/mL,24-72 小时) 在浓度高达 100 μg/mL、作用 72 小时后对人牙龈成纤维细胞 (HFG-1) 无细胞毒性[1]
D-Cateslytin (100-123 μM,24 小时) 在白色念珠菌上清液和人唾液中均能保持稳定[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: HFG-1 cells
Concentration: 0-100 μg/mL
Incubation Time: 24, 48 and 72 h
Result: Showed no cytotoxicity on HGF-1 after 72 hours for concentrations up to 100 μg/mL.
分子量

1860.15

Formula

C81H130N30O19S

CAS 号
Sequence

d-{Arg-Ser-Met-Arg-Leu-Ser-Phe-Arg-Ala-Arg-Gly-Tyr-Gly-Phe-Arg}

Sequence Shortening

d{RSMRLSFRARGYGFR}

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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D-Cateslytin
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HY-P11170
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