2. Anti-infection
  3. HBV
  4. Daplusiran sodium

Daplusiran sodium 是 JNJ-3989 中的一种 siRNA。JNJ-3989 由两个 siRNA（Daplusiran 和 Tomligisiran）组成，能够针对乙型肝炎病毒（HBV）的 mRNA 进行降解，从而抑制 HBV 的复制。

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RNA, (Am-sp-(2'-deoxy-2'-fluoro)G-sp-Am-sp-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)A-Um-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)G-Um-(2'-deoxy-2'-fluoro)C-Cm-Am-sp-Cm), complex with RNA ([1'-de(6-amino-9H-purin-9-yl)]dA-(5'→5')-sp-Gm-Um-Gm-Gm-Am-Cm-Um-Um-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)C-Um-Cm-Am-Am-Um-Um-Um-Um-Cm-Um-(3'→3')-sp-[1'-de(6-amino-9H-purin-9-yl)]dA) 3'-[O-[cis-4-[(3S,8S)-17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,8-bis[[[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]amino]carbonyl]-1,6,11-trioxo-15-oxa-2,7,12-triazaheptadec-1-yl]cyclohexyl] hydrogen phosphorothioate] (1:1), sodium salt

Daplusiran sodium Chemical Structure

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Daplusiran sodium 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DaplusiranHBVHepatitis B virusInhibitorinhibitorinhibit

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产品名称：
Daplusiran sodium
目录号：
HY-177625A
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