2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. Nucleoside Antimetabolite/Analog Dihydropyrimidine Dehydrogenase (DPD)
  4. DFP-11207

DFP-11207 是一种具有口服活性的氟嘧啶类细胞毒性试剂。DFP-11207 将 5-FU (HY-90006) 前药与可逆的 DPD 抑制剂以及强效的 OPRT 抑制剂相结合，从而增强了 5-FU 的药理活性，同时降低了胃肠道毒性和骨髓抑制毒性。DFP-11207 可用于癌症研究。

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DFP-11207

DFP-11207 Chemical Structure

CAS No. : 1296177-16-6

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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DFP-11207 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DFP-11207 is an orally active fluoropyrimidine cytotoxic agent. DFP-11207 combines a 5-FU (HY-90006) pro-drug with a reversible DPD inhibitor and a potent inhibitor of OPRT, resulting in enhanced pharmacological activity of 5-FU with decreased gastrointestinal and myelosuppressive toxicities. DFP-11207 can be used for the research of cancer [1].

分子量

713.02

Formula

C32H26ClFN4O12
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

DFP-11207 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DFP-112071296177-16-6DFP11207DFP 11207Nucleoside Antimetabolite/AnalogDihydropyrimidine Dehydrogenase (DPD)Dihydropyrimidine DehydrogenaseFluoropyrimidinecytotoxic agentchemotherapy5-FUDPD inhibitorOPRT inhibitorcancerInhibitorinhibitorinhibit

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产品名称：
DFP-11207
目录号：
HY-114249
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