Glioblastoma  (胶质母细胞瘤)

胶质母细胞瘤是一种起源于星形胶质细胞的高度侵袭性恶性脑肿瘤，其特征是快速浸润周围脑组织、坏死、异常血管形成以及多形性间变性细胞。它是最常见且最致命的原发性脑癌，预后不良，常表现为非特异性症状，例如头痛、恶心、嗜睡、性格改变和类似中风的神经功能障碍。虽然确切病因尚不清楚，但罕见情况下与遗传综合征存在关联。

Glioblastoma is a highly aggressive and malignant brain tumor arising from astrocytes, characterized by rapid infiltration into surrounding brain tissue, necrosis, abnormal blood vessel formation, and pleomorphic, anaplastic cells. It is the most common and deadly primary brain cancer, with a poor prognosis, often presenting with nonspecific symptoms such as headaches, nausea, drowsiness, personality changes, and stroke-like neurological deficits. While the exact cause remains largely unknown, rare associations exist with genetic syndromes.

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