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  3. DL-Poly(lactic acid)

DL-Poly (lactic acid) 是一种可生物降解的聚 (α-羟基酸) 基质,是一种用于药物控释的包衣材料。DL-Poly (lactic acid) 可被定性为释药阻滞剂,能降解为碳水化合物代谢中间产物天然乳酸单体,可实现持续数周的完整药物递送,其释药速率受周围环境 pH 影响。

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DL-Poly(lactic acid)

DL-Poly(lactic acid) Chemical Structure

CAS No. : 26023-30-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DL-Poly (lactic acid) is a biodegradable poly (α-hydroxy acid) matrix and a coating material for controlled drug release. DL-Poly (lactic acid) is classified as a drug release retardant, which degrades into natural lactic acid monomers, an intermediate product of carbohydrate metabolism, enabling complete drug delivery that lasts for several weeks. Its drug release rate is affected by the pH of the surrounding environment[1][2].

体外研究
(In Vitro)

DL-poly (lactic acid) 骨架片通过扩散与聚合物降解相结合的机制,可在 40 天内实现 Diclofenac Sodium (HY-15037) 的完全释放 (在 pH 7.4 条件下释放更快),并在 60 天内实现 Propranolol (HY-B0573B) 的部分至接近完全释放 (在 pH 5.4 条件下 35 天后释放速度加快)[1]
DL-Poly (lactic acid)-coated microcapsules 可延缓 Cyclazocine 的释放[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

102.13

Formula

C5H10O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

DL-Poly(lactic acid) 相关分类

  • 摩尔计算器

  • 稀释计算器

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产品名称:
DL-Poly(lactic acid)
目录号:
HY-W583729
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