2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor Membrane Transporter/Ion Channel
  3. LXR ATP-binding cassette (ABC) transporters
  4. E17110

E17110 是一种肝 X 受体 β (LXRβ) 激动剂，其 EC50 值为 0.72 μM。E17110 能够增加 RAW264.7 巨噬细胞中 ATP 结合盒转运蛋白 A1 (ABCA1) 和 G1(ABCG1) 的表达。E17110 还可减少细胞内脂质蓄积并促进胆固醇外流。E17110 可用于心血管疾病的研究，如动脉粥样硬化。

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E17110

E17110 Chemical Structure

CAS No. : 1090785-30-0

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E17110 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

E17110 is a liver X receptor β (LXRβ) agonist with an EC50 of 0.72 μM. E17110 can increase the expression of ATP-binding cassette transporter A1 (ABCA1) and G1 (ABCG1) in RAW264.7 macrophages. E17110 also reduce cellular lipid accumulation and promoted cholesterol efflux. E17110 can be used for the research of cardiovascular disease, such as atherosclerosis[1].

分子量

334.30

Formula

C16H15FN2O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

E17110 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

E171101090785-30-0E 17110E-17110LXRATP-binding cassette (ABC) transportersLiver X receptorATP-binding cassette transportersInhibitorinhibitorinhibit

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